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Although cagrilintide-semaglutide produced greater weight loss than either monotherapy alone in REDEFINE 1, the study design does not permit a formal assessment of pharmacological additivity or synergy

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Furthermore, we posit that cancer cells that are intrinsically resistant to redox modulation facilitate a cellular state in which observations of the p53 mutant-specific rescue effects of APR-246 can be observed

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Zhang YS, Zheng YD, Yuan Y, Chen SC, Xie BC

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