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Further studies have investigated the compound in body composition, bone density, and sleep architecture research in preclinical models

Studies suggest direct benefits on the heart muscle cells (cardiomyocytes), such as reducing oxidative stress and inhibiting cell death, which can protect against myocardial injury (like during a heart attack)

However, it's best to avoid layering GHK-Cu with highly acidic ingredients (like L-ascorbic acid Vitamin C) or strong exfoliants (like AHAs/BHAs and retinoids) in the same application

If administered by injection, local reactions such as redness, swelling, itching, or pain can occur, and improper technique can increase infection risk