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systematic review of 13 studies encompassing 84,065 patients demonstrated significantly higher retained gastric contents rates (odds ratio 5.56, 95% confidence interval 3.359.23) but found no significant difference in actual aspiration rates (odds ratio 1.75, 95% confidence interval 0.644.77) [37]
Across these investigations, most studies report therapy-associated microbial compositional changes, whereas only a limited number have specifically explored baseline microbiome features associated with treatment response
Moreover, several bioactive compounds found in fish, such as n-3 polyunsaturated fatty acids, taurine, and other active substances, may contribute to the health benefits of seafood