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Por otra parte si su origen es endocrino pueden ser indicativas de una alteracin fisiolgica, indica Jimnez-Castellanos

Methylmalonic acid (MMA): A more sensitive marker of B12 function

Kovacs DM

Conventional diagnostic pathways remain largely anchored in clinical guidelines, neuroimaging, and basic cognitive tests such as the Montreal Cognitive Assesment (MoCA), the Mini-Mental State Examination (MMSE) or disease-specific questionnaires like the Parkinsons Disease Questionnaire-39 (PDQ-39) (Folstein et al., 1975