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Department of Endocrinology, Mymensingh Medical College, Charpara, Mymensingh Sadar, Mymensingh 2200, Bangladesh Tel: +880-1711103905, Fax: +880-9166064, E-mail: [email protected] Received: September 29, 2024 Revised: October 11, 2024 Accepted: November 14, 2024 Copyright 2025 Korean Endocrine Society This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited

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Until proper human trials are conducted, users are essentially volunteering as test subjects in an uncontrolled experiment with their own bodies.

An enzyme called NNMT (nicotinamide N-methyltransferase) drains the NAD+ salvage pathway by methylating nicotinamide, one of NAD+'s precursors