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Structural modifications extend its half-life and reduce binding to IGF-binding proteins, allowing prolonged receptor interaction
Despite the enormous success of the Hib-conjugate vaccine in preventing invasive infections caused by capsular type b H.influenzae , it has no effect on NTHi because these strains lacks the type b capsule (the vaccine target) (Hariadi et al., 2015)
Strikingly, the synthesis and functional pathways of GPX4 are essential in regulating ferroptosis
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