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The Overall Hospital Quality Star Rating methodology would be unchanged through step eight with the exception of redesignating paragraph (d)(5) as (6), and paragraph (d)(6) as (5) (assignment of star ratings using K-means clustering as described previously in this section), with the cap being applied as a new step nine: Any hospital that is assigned 5 stars in step eight but has a lowest quartile Safety of Care score (based on at least three Safety of Care measures) would be reassigned to 4 stars

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Unlike exogenous GH administration, sermorelin preserves physiologic feedback loopsGH release is subject to normal negative feedback via somatostatin and IGF1, reducing the risk of excessive GH or IGF1 levels [6]