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B12 deficiencies are usually a result of diet, especially among vegans, this is because we can only get vitamin b12 through foods such as meat, fish and dairy products, our bodies do not produce it

Therefore, this study aimed to compare two intranasal vitamin B12 dosage regimens (with and without loading dose) in elderly patients deficient in vitamin B12, focusing on vitamin B12 levels and three biomarkers indicative of deficiency: holotranscobalamin, methylmalonic acid, and total homocysteine

The presence of visible crystals does not mean the product is defective, degraded, or unusable for research handling