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In another study, the same treatment in 19 participants with obesity and diabetes was associated with an improved MoCA score, olfactory test total score and enhanced odor-induced right parahippocampus activation 46

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Factors That Affect the Duration of Tiredness Dose escalation speed, nutritional adequacy, hydration status, pre-existing conditions such as anaemia or hypothyroidism, and sleep quality all influence how long retatrutide-related fatigue persists