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For example, at a very conservative guestimate (taking the lowest of the range of hydrogen bond energies above 12 kJ/mole and just a thousand water molecules associated with a proteins hydrophilic domains), one arrives at a figure of around 12,000 kJ/mole for their collective energy (assuming each water molecule forms just one hydrogen bond with a neighbour or the protein: a water molecule can form up to four hydrogen bonds with its neighbours [Jorgensen and Madura, 1985])

Campos LD, Almeida SantosPinentel VJD Jr, Carrega GLF, Cazarin CBB

The sugar content in Sprite can provide a quick source of energy, which may be beneficial when someone is feeling weak or fatigued due to an upset stomach

Jonas AJ, Conley SB, Marshall R, Johnson RA, Marks M, Rosenberg H (1987) Nephropathic cystinosis with central nervous system involvement