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Longer follow-up will be required because all but 47 patients were alive at the time of analysis, and there was a crossover to the study drug on progression from placebo, making analysis of OS problematic

In the Phase 3 database, the mean HbA1c increase was approximately 0.1 to 0.2 percent at 52 weeks, clinically minor for most subjects but relevant for anyone with pre-existing insulin resistance or type 2 diabetes

To answer the first question, we transplanted tumors lacking the ability to produce GSH (Gclc-KO) into wild-type mice and, surprisingly, the tumors grew normally

How does retatrutide differ clinically from tirzepatide or semaglutide