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[5] Even when fiber intake is adequate, several factors can impair butyrate production: [6] Microbiome disruption from antibiotics, stress, or illness Age-related decline in butyrate-producing bacteria Rapid transit time limiting fermentation Individual variation in bacterial composition Competition from other bacterial metabolic pathways This production variability explains why some people experience dramatic benefits from increasing fiber intake while others see little change despite their best efforts

A race for MASH drug development Resmetirom (Rezdiffra), a liver-targeted THR- receptor agonist, marked the first major milestone in drug development for MASH

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This is why we recommend mixing it into a post-workout shake or taking it with a meal that includes some healthy carbohydrates