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On the test day, 7 consecutive trials of 2 min per trial (with 1-min intertrial intervals) were undertaken with the following set speeds: 12, 16, 20, 25, 30, 35, and 40 rpm

Nrf2 depletion in macrophages leads to increased foam cell formation, increases the M1 inflammatory phenotype with enhanced expression of pro-inflammatory monocyte chemoattractant protein-1 and interleukin-6, and aggravates atherosclerosis (244, 245)

The controls were survivors of critical COVID-19 who fully recovered without dyspnea, cognitive impairment or fatigue at the same timepoint