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International journal of Preventive Medicine, 9, 101

It was speculated that this increase in DR risk with semaglutide OW in SUSTAIN 6 was due to the large and rapid reduction in HbA 1c levels, as observed with other existing therapies [58]

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Experiments measuring glucose-stimulated GIP secretion after inhibiting chylomicron release (Pluronic 818) or basolateral hydrolysis of chylomicrons (poloxamer-407) may help delineate the exact contribution of each nutrient