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EGCG as a chemopreventive agent can modulate angiogenesis and apoptosis by downregulation of various signaling pathways such as Vascular Endothelial Growth Factor (VEGF), Epidermal Growth Factor Receptor (EGFR) and cell cycle regulatory proteins such as Mitogen-activated protein kinases (MAPK) (Shankar et al
2001 Mar
More serious side effects that should prompt medical attention are increased blood pressure, heart palpitation, chest pain, shortness of breath, and swelling of the legs and ankles
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