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Most important of these was Novo Nordisk demonstrating in a 17,000 patient five year clinical trial that Wegovy reduced the risk of major cardiovascular events (MACE) by 20%

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Dietary restraint LSM changes from baseline in Dietary Restraint scores were generally not different at Week 24 or 36 in any treatment group, except for increases in the retatrutide 12 mg group (Week 24 LSM change 2.0