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Decreases in triglyceride-rich lipoproteins reduce both atherosclerotic risk and acute pancreatitis risk in susceptible individuals
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Combining GIP and GLP-1R agonism was first discovered and reported a decade ago 40 and has now fully evolved as the GIP/GLP-1R co-agonist tirzepatide that can achieve more than 20% weight loss in obesity as well as offering superior benefits in diabetes
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