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Similarly, other studies have noted that while higher rates of preterm birth and neonatal complications are observed, these outcomes appear comparable to those in insulin-exposed pregnancies, suggesting a stronger influence of underlying maternal metabolic disease than drug-specific effects [17, 18]

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We have indicated that male mice could also successfully establish NTG induced CM model [17, 18], it is well known that sex differences in migraine is mainly due to the role of estrogen [44, 45], thus, to avoid the influence of estrogen, we selected male mice for further study

This remains a rationale, not a tested clinical outcome in GLP-1 medication users