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Supplementary Information Supplemental chemical schema and results include hydrogel swell behavior in isotonic PBS, agar-well diffusion data against carbapenem-susceptible P

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As mechanistic insights into iron homeostasis, lipid peroxidation, and immunometabolic interactions continue to deepen, alongside progress in drug delivery, gene editing, and regenerative medicine, therapies targeting ferroptosis may represent a promising new paradigm in OA management, ultimately enhancing joint function and overall quality of life for affected individuals