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According to FDA prescribing information, patients have considerable flexibility regarding the time of day they administer their weekly injection
Outcome Focus: The trials were designed primarily to assess weight loss efficacy, with safety as a secondary outcome
Acta 1830 , 31733181, (2013)
QA accumulation is associated with brain inflammation and cell death, and patients with advanced CKD exhibit elevated plasma KYN metabolites and QA, which uniquely correlate with fatigue and reduced quality of life (Saliba et al., 2024), supporting the role of gut-derived KYN metabolites in linking CKD to neuroinflammation
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