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Tirzepatide is administered as a once-weekly subcutaneous injection, with doses typically starting at 2.5 mg for initiation (not for glycemic control)

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CONCEPT OF TWINCRETINS IN MANAGEMENT OF TYPE 2 DIABETES It has been postulated that the glucose-lowering effects of simultaneous GLP-1R agonism might help overcome resistance to GIP action in T2D, thus enabling greater glucose-lowering effects when combined