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Semaglutide (Wegovy) and tirzepatide (Zepbound) have FDA approval for chronic weight management, which provides an independent prescribing pathway for women with PCOS and overweight or obesity

However, observed weight gains were marginally lower than those seen with the comparator medications in the clinical studies [54, 55]

Yan H, Peng Z, Zhang H, Wang B, Xu W, He Z (2025) Cadmium minimization in crops: a trade-off with mineral nutrients in safe breeding