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Patients who are less than 18 years old Pregnant/breastfeeding/ planning to become pregnant Type 1 diabetes mellitus Diabetes ketoacidosis Hypersensitivity to semaglutide or any components of this medication Personal or family history of medullary thyroid carcinoma History of multiple endocrine neoplasia syndrome History pancreatitis End stage renal disease (on dialysis) Patients with diabetic retinopathy Patients with a history of anaphylaxis or angioedema Caution in patients: Type 2 diabetic patients that are on insulin or a sulfonylurea- due to increased need for glucose monitoring

10 They can be administered via subcutaneous injection or orally