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All three are also indicated for diabetes under different names and dosing schedules, which can be confusing (see the table GLP Agonists for Obesity)

Higher-dose versions like Wegovy and Zepbound have received FDA approval specifically for obesity, fueling a market expected to boom from $2.8 billion in 2022 to over $100 billion by 2030

A 2025 randomized, double-blind, placebo-controlled trial published in Clinical Nutrition found that 15 mg/day of hydroxytyrosol improved antioxidant and anti-inflammatory status in overweight individuals with prediabetes over 16 weeks, while preserving insulin sensitivity (Moratilla-Rivera et al., 2025)

Hispanic patients followed a similar trend