The incremental number of QALYs associated with SGLT2i use was projected at 29,357, and widespread use of SGLT2is was projected to lead to an incremental healthcare cost of AU$0.3 billion, resulting in an ICER of AU$8878 per QALY gained

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10.3390/toxins14090605 4 Alassane-KpembiI.PintonP.OswaldI
In addition to an assessment of semaglutide exposure levels, the aim of the present analysis was to provide additional details of the PK properties of semaglutide in terms of absorption, distribution and elimination and their relationships to covariate factors, in order to develop a novel disposition model that would be generally applicable across different routes of administration