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In addition, the observed side-chain flexibility of V12 and F112 indicated that these residues are mainly involved in the overall shaping of the active site and help to position the flavonoid substrate in accordance with the presented structural evidence
Materials and methods Materials and reagents Raw camel milk was aseptically collected from free-ranging primiparous Bactrian camels in Ulan County, Qinghai Province, China, in May 2024
In CuCP complex, which constitutes approximately 75% from the total copper pool (our data and 4,5 ), the copper ions are bound in protein interior, which makes them kinetically inert and practically nonexchangeable at physiological pH values even in the presence of high millimolar concentrations of powerful Cu(II)-chelating ligands like EDTA or DTPA
Due to the low molecular weight of TB-500, it is extremely mobile
