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Studies also demonstrated no significant inference of MTHFR C677T polymorphism in global DNA methylation in oral epithelial cell samples 31 or lymphocytes of healthy individuals 32 , as well as cutaneous squamous cell carcinoma in renal transplant patients 33

Notably, it has been reported that ghrelin infusion can increase food intake in healthy volunteers 67 and in patients with anorexia due to cancer 68 and chronic renal failure