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For some, side effects are severeespecially at the higher doses needed to achieve their health goals

[25] This appraisal is useful context for understanding how similar agents are evaluated in the UK, but it does not apply directly to retatrutide, which remains unlicensed

Among these, the ketogenic (keto) diet, which peaked in 2020 and subsequently dropped off, has maintained, and even gained popularity for its potential to induce lasting weight loss and improve metabolic health