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La WADA (Agencia Mundial Antidopaje) lo incluye en lista de sustancias prohibidas para deportistas competitivos desde 2019

Specifically, blocking the 1-adrenergic receptors with prazosin or the opioid receptors with nalbuphine interfered with the ability of GLP-1RAs to reduce plasma TNF- levels, indicating the critical importance of these pathways in the anti-inflammatory effects mediated by GLP-1 activation

The peptide sequence (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val) is entirely stable in an aqueous solution, a property that distinguishes it from many other peptides that degrade rapidly in the gut or bloodstream