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Anticoagulants may increase the risk of bleeding, so regular follow-up and communication with a healthcare provider are essential

15 Phase II trials targeting MASH have shown that treatment with SEMA 0.4 mg daily for 72 weeks resulted in more patients with liver fibrosis stage F2/F3 achieving improvement in MASH without progression of liver fibrosis (odds ratio = 6.87, 95% CI = 2.6017.63) compared to placebo

L-carnitine is not directly associated with overall metabolism

For example, naltrexone is contraindicated for individuals who are currently taking opioid pain medications or those who have acute hepatitis or liver failure