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Alzheimer's Dement

iPSC-derived microglia were obtained first from homogeneous and stable embryonic bodies (EB), and after 30 days, macrophage precursors were differentiated into microglia in the presence of IL-34, M-CSF, and TGF-1 (Reich et al., 2020)

They detected a notable fluorescent signal exclusively in the arcuate nucleus (ARC) and ME in mice that received peripheral administration of fluorescein-ghrelin at a low dose (55)