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Throughout the experiment, animals were maintained under anaesthesia, and artificial cerebrospinal fluid (NaH 2 PO 4 2.0 mM, MgCl 2 1.0 mM, CaCl 2 1.2 mM, KCl 2.7 mM and NaCl 145 mM) was constantly pumped through the microdialysis probe at a rate of 0.5 L/min

These effects are mediated through several mechanisms, including metabolic stimulation, appetite regulation, inhibition of digestive enzymes, improving in insulin sensitivity, and direct action on fat storage and breakdown processes

Summary: Palpitations are not listed as a common adverse effect of Wegovy in UK prescribing information, though some patients may perceive the modest heart rate increase (14 beats per minute) as palpitations

Appl Clin Genet