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Some people become B12 deficient due to other reasons such as a medical condition or alcohol misuse

However, prolonged or high-dose ketamine exposure induces a compensatory upregulation of NMDARs, increasing intracellular calcium ion influx and ROS production, ultimately leading to neuronal apoptosis ( In animal studies, antagonism of NMDA receptors in intermediate neurons of the forebrain and thalamus reduces GABAergic function

This is a meaningful mechanistic observation that contributes to the broader fat-loss narrative around the compound

Increases Blood Circulation By improving angiogenesis, BPC-157 enhances blood circulation throughout the body