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There are several pharmacological treatments available to augment insulin secretion or reduce peripheral tissue insulin resistance in addition to patients adopting a healthier diet and increased exercise to achieve weight loss, which promotes normoglycaemia and alleviates the disease phenotype

The Role of Prescribers in Closing the Gap The gap between what the clinical evidence supports and what patients typically receive as guidance when they are prescribed a GLP-1 is, in my experience, significant

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Its extended half-life of approximately 2030 hours allows for less frequent dosing compared to standard IGF-1, with protocols typically running 46 weeks followed by an equal washout period to prevent receptor desensitization