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Ozempic and Mounjaro work through different mechanisms, which means maintenance strategies may differ

Next-generation GLP-1/GIP/glucagon triple agonists

Subsequently, the IL-10 receptor/STAT3 signaling pathway in microglia is autocrinally activated, thereby promoting the expression and release of -endorphin, the latter acts on -opioid receptors on neurons to produce analgesic and neuroprotective effects (103105)