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Almost comparable to whats seen with some surgical interventions: Participants lost up to 20.9% of their body weight on the highest dose (15 mg) 91% lost at least 5% of their body weight More than half lost 20% or more, and over a third dropped 25% or more Waist size, blood pressure, insulin resistance, and cholesterol all improved Most side effects (like nausea or constipation) were mild and appeared mostly during the dose adjustment phase

1.1 Incidence and prevalence Post-bariatric hypoglycemia (PBH) is a recognised complication of bariatric surgery, but the precise incidence and prevalence is still not fully understood [18]

then Metformin is started in addition to subcutaneous insulin therapy for a few weeks and then a decision is made as to whether insulin can be weaned or stopped with continued Metformin treatment (96)

the overall IMFs is therefore stronger, leading to a higher boiling point