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Endometriotic implants secrete estradiol (E2) as well as prostaglandin E2 (PGE2), agents that attract macrophages (monocyte chemotactic protein 1[MCP-1]), neurotrophic peptides (nerve growth factor [NGF]), enzymes for tissue remodeling (matrix metalloproteinases [MMPs]) and tissue inhibitors of MMPs (TIMPs), and proangiogenic substances such as vascular endothelial growth factor (VEGF) and interleukin-8 (6)

Wright: [00:29:01] Can you talk to us about a little bit of the potential interactions that are like maybe the top two or three interactions that GLP-1 medications may have with other drugs, or I know it's probably on a case by case basis because everybody takes something different, but maybe some primary ones to look out for

Oral spray makes sense, especially with advanced delivery technology

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