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Bioavailability refers to the amount of a substance that actually enters the bloodstream and becomes available for use by the body

The presence of translation-inhibiting secondary structures within the 5 UTR of mRNA transcripts has been previously demonstrated [82, 86], and designing ASOs that are complementary to these regions, could potentially relieve translational inhibition (Fig

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During monotherapy evaluation of epilepsy in pediatric patients 6 to 15 years of age, the following effects occurred in patients receiving topiramate 50 mg per day vs