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Clinical data show that gastrointestinal symptomsincluding indigestion, nausea, and bloatingoccur frequently, particularly during initial treatment or dose increases

In an 8-week-old Apoe knock-out mouse model, the group of mice receiving Lactobacillus reuteri strain ATCC PTA 4659 indicated a significant reduction in body weight, adipose, and liver weight, and decreased serum insulin levels, attributing to increased -oxidation

PMID 16374859