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- Participants: 29 healthy adults

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More specifically, when NT binds to Trk receptors, three enzymes are considered to be the main regulators: mitogen-activated protein kinase (MAPK), phosphatidylinositol-3 kinase (PI3K) (33) and phospholipase C (PLC) (34)

Alternatively, the copper ion may contribute independently of the peptide, or the clinical effects may be mediated through surface-level signaling that does not require deep penetration