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A recent systemic review and meta-analysis published in the British Medical Journal (BMJ) found that while people tend to lose more weight more quickly with GLP-1s compared to traditional behavioral weight loss programs like exercise and diets, they may gain weight back faster after they stop taking the drugs compared to after they stop these lifestyle changes

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However, compounded medications are legally allowed only when the branded drug is on the FDAs shortage list , as is the case with Ozempic, due to high demand