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Browning of WAT is a process of trans-differentiation from white to beige adipocytes, involving mitochondrial biogenesis, uncoupling of the mitochondrial respiratory chain and switch from energy accumulation to energy dissipation

Whether treatment with semaglutide would mitigate these risks is unknown

They are not suitable for everyone and must be prescribed and monitored by a healthcare professional, as side effects can include nausea, gastrointestinal discomfort, and more serious complications in rare cases

The most common overdose symptoms include severe nausea lasting hours, persistent vomiting that prevents you from keeping food or water down, and abdominal pain that radiates across your stomach and sides