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Comparative trials show that long-acting medications (exenatide once weekly, liraglutide, dulaglutide, and semaglutide) provide better glycemic control than short-acting medications (exenatide twice daily and lixisenatide) [90]

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So, it can reduce macrophage infiltration of adipose tissue, inhibit inflammatory pathways in adipocytes and ameliorate insulin sensitivity (98)