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The studys co-primary endpoints are changes in HRQoL and the composite of cardiovascular death and HF events
It is important to emphasize that if shortness of breath develops during GLP-1 treatment, it should not be automatically attributed to the medication without thorough clinical evaluation
Those are pharmaceutical drugs
Furthermore, exendin-4 has been shown to attenuate lipotoxicity-induced glomerular endothelial cell dysfunction in diabetic ApoE-deficient mice by increasing the ABC transporter A1-mediated cholesterol efflux (Yin et al., 2016)
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