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15 In mammals, this process is catalyzed by enzymes encoded by genes such as CntA/B, CutC, and betaine reductase

[200] [202] As of January 2026, protein kinase A (PKA), protein kinase C (PKC), Ca2+/calmodulin-dependent protein kinase II (CaMKII), and Ras homolog family member A (RhoA) have all been demonstrated experimentally to regulate monoamine transporter function activity following amphetamine exposure

On the one hand, they regulate some of the most conserved and powerful physiological processes in humans, including stress adaptation, reproduction, inflammation, autonomic control, and tissue repair

Significa eso que, para la gran mayora de las personas, estos medicamentos no pueden tener efectos duraderos y poner la obesidad en remisin