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An air bubble in your syringe means you are injecting less medication than your dose marking indicates

J Gastroenterol Hepatol Res 5:21912195 An JH, Kim YJ, Kim KJ, Kim SH, Kim NH, Kim HY, Kim NH, Choi KM, Baik SH, Choi DS (2016) L-carnitine supplementation for the management of fatigue in patients with hypothyroidism on levothyroxine treatment: a randomized, double-blind, placebo-controlled trial

How Patent Term Extension Works for Drug-Device Products PTE can add up to five years to a qualifying patents term, limited so that the total post-approval exclusivity period does not exceed 14 years