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The colon transit period (normal is 59 hours or less) is calculated from the time the WMC enters the cecum till it is expelled from the body, as indicated by a sudden drop in temperature or signal loss

The ongoing second part of the study is evaluating MariTide beyond 52 weeks, looking at additional weight loss with continued treatment, weight maintenance using less frequent or lower dosing and durability of weight loss following treatment discontinuation

It was later recognised that K ATP -dependent and K ATP -independent GSIS are coordinated to ensure the maximum secretion of insulin in response to glucose [2]

Wegovy preferred for obesity, Zepbound moved to non-formulary for obesity as of July 2025