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The Power of Combination: The S-LiTE Trial Research published in JAMA Network Open (Sandsdal et al., 2023) and The Lancet Healthy Longevity (Jensen et al., 2026) compared GLP-1 use alone versus GLP-1 plus exercise: Body Composition: The "Exercise + GLP-1" group reduced abdominal fat by 6.1% , nearly double the results of the medication-only group

Uhl P, Bajraktari-Sylejmani G, Witzigmann D, Bay C, Zimmermann S, Burhenne J, et al

Global epidemiology of nonalcoholic fatty liver disease-meta-analytic assessment of prevalence, incidence, and outcomes

In fact, GLP-1 RAs of all stripes have some common side effects worth mentioning, as well as some increased risk factors for other diseases