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The Treatment Imperative: Effectively managing obesity is now recognized as a primary strategy to curb the rise of T2D and its life-threatening complications

Uric acid is a by-product of that process, which can lead to increased levels in the bloodstream

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cAMP directly activates protein kinase A (PKA) and cAMP-regulated guanine nucleotide exchange factor 2 (Epac2), that act synergistically to generate downstream signals resulting in increased insulin secretion (8)