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Distinct regions in the C-Terminus required for GLP-1R cell surface expression, activity and internalisation

Platelets can contact LSECs to induce LSEC proliferation and secrete VEGF and IL-6 via sphingosine 1-phosphate (S1P)

Singh P, Alex JM, Bast F

mutation of residues within the predicted receptor-cholesterol binding sites caused changes in basal receptor activity, ligand binding, G protein coupling and cAMP responses (21)